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| Interactions: | Amiodarone
Adverse Effect: hypotension bradycardia or cardiac arrest Clinical Management: Monitor cardiac function carefully. Amiodarone should be used with caution in patients receiving beta blockers particularly if there is suspicion of underlying dysfunction of the sinus node such as bradycardia or sick sinus syndrome or if there is partial AV block.
Amlodipine
Adverse Effect: hypotension and/or bradycardia Clinical Management: If concurrent therapy is required monitor cardiac function carefully particularly in patients predisposed to heart failure.
Benidipine
Adverse Effect: hypotension and/or bradycardia Clinical Management: If concurrent therapy is required monitor cardiac function carefully particularly in patients predisposed to heart failure.
Celecoxib
Adverse Effect: Decreased antihypertensive effect Clinical Management: If concurrent therapy is required monitor the patients blood pressure carefully and assess the need for a dosage adjustment for the beta blocker.
Digoxin
Adverse Effect: AV block and possible digoxin toxicity Clinical Management: When beta blockers and digoxin are to be given concomitantly carefully monitor ECG and digoxin serum concentrations. Adjust doses accordingly.
Diltiazem
Adverse Effect: Hypotension bradycardia AV conduction disturbances Clinical Management: If concurrent therapy is required monitor cardiac function carefully particularly in patients predisposed to heart failure. A dosage adjustment for hepatically metabolized beta blockers may be required.
Felodipine
Adverse Effect: hypotension and/or bradycardia Clinical Management: If concurrent therapy is required monitor cardiac function carefully particularly in patients predisposed to heart failure.
Fentanyl
Adverse Effect: Severe hypotension Clinical Management: Concurrent use of a calcium channel blocker and a beta-adrenergic blocker during fentanyl anesthesia has been reported to result in severe hypotension.
Flunarizine
Adverse Effect: Hypotension bradycardia and AV conduction disturbances Clinical Management: If concurrent therapy is required monitor cardiac function carefully particularly in patients predisposed to heart failure or bradyarrhythmias.
Flurbiprofen
Adverse Effect: Decreased antihypertensive effect Clinical Management: If concurrent therapy is required monitor the patients blood pressure carefully and assess the need for a dosage adjustment for the beta blocker.
Ibuprofen
Adverse Effect: Decreased antihypertensive effect Clinical Management: If concurrent therapy is required monitor the patients blood pressure carefully and assess the need for a dosage adjustment for the beta blocker.
Ibuprofen Comb.
Adverse Effect: Decreased antihypertensive effect Clinical Management: If concurrent therapy is required monitor the patients blood pressure carefully and assess the need for a dosage adjustment for the beta blocker.
Indomethacin
Adverse Effect: Decreased antihypertensive effect Clinical Management: If concurrent therapy is required monitor the patients blood pressure carefully and assess the need for a dosage adjustment for the beta blocker.
Ketoprofen
Adverse Effect: Decreased antihypertensive effect Clinical Management: If concurrent therapy is required monitor the patients blood pressure carefully and assess the need for a dosage adjustment for the beta blocker.
Ketorolac
Adverse Effect: Decreased antihypertensive effect Clinical Management: If concurrent therapy is required monitor the patients blood pressure carefully and assess the need for a dosage adjustment for the beta blocker.
Lacidipine
Adverse Effect: hypotension and/or bradycardia Clinical Management: If concurrent therapy is required monitor cardiac function carefully particularly in patients predisposed to heart failure.
Lidoflazine
Adverse Effect: Hypotension bradycardia and AV conduction disturbances Clinical Management: If concurrent therapy is required monitor cardiac function carefully particularly in patients predisposed to heart failure or bradyarrhythmias.
Mefenamic Acid
Adverse Effect: Decreased antihypertensive effect Clinical Management: If concurrent therapy is required monitor the patients blood pressure carefully and assess the need for a dosage adjustment for the beta blocker.
Meloxicam
Adverse Effect: Decreased antihypertensive effect Clinical Management: If concurrent therapy is required monitor the patients blood pressure carefully and assess the need for a dosage adjustment for the beta blocker.
Methyldopa
Adverse Effect: Exaggerated hypertensive response tachycardia or arrhythmias during physiologic stress or exposure to exogenous catecholamines Clinical Management: Monitor blood pressure carefully during concurrent therapy especially during excessive physiologic stress or use of exogenous catecholamines such as phenylpropanolamine.
Morphine
Adverse Effect: Esmolol toxicity (bradycardia hypotension) Clinical Management: It is suggested that although morphine may elevate steady-state levels of esmolol any subsequent side effects can be titrated by lowering the esmolol infusion rate.
Nabumetone
Adverse Effect: Decreased antihypertensive effect Clinical Management: If concurrent therapy is required monitor the patients blood pressure carefully and assess the need for a dosage adjustment for the beta blocker.
Naproxen
Adverse Effect: Decreased antihypertensive effect Clinical Management: If concurrent therapy is required monitor the patients blood pressure carefully and assess the need for a dosage adjustment for the beta blocker.
Nifedipine
Adverse Effect: hypotension and/or bradycardia Clinical Management: If concurrent therapy is required monitor cardiac function carefully particularly in patients predisposed to heart failure.
Nimesulide
Adverse Effect: Decreased antihypertensive effect Clinical Management: If concurrent therapy is required monitor the patients blood pressure carefully and assess the need for a dosage adjustment for the beta blocker.
Nitrendipine
Adverse Effect: hypotension and/or bradycardia Clinical Management: If concurrent therapy is required monitor cardiac function carefully particularly in patients predisposed to heart failure.
Oxyphenbutazone
Adverse Effect: Decreased antihypertensive effect Clinical Management: If concurrent therapy is required monitor the patients blood pressure carefully and assess the need for a dosage adjustment for the beta blocker.
Paracetamol
Adverse Effect: Decreased antihypertensive effect Clinical Management: If concurrent therapy is required monitor the patients blood pressure carefully and assess the need for a dosage adjustment for the beta blocker.
Paracetamol Comb.
Adverse Effect: Decreased antihypertensive effect Clinical Management: If concurrent therapy is required monitor the patients blood pressure carefully and assess the need for a dosage adjustment for the beta blocker.
Phenacetin
Adverse Effect: Decreased antihypertensive effect Clinical Management: If concurrent therapy is required monitor the patients blood pressure carefully and assess the need for a dosage adjustment for the beta blocker.
Phenylbutazone
Adverse Effect: Decreased antihypertensive effect Clinical Management: If concurrent therapy is required monitor the patients blood pressure carefully and assess the need for a dosage adjustment for the beta blocker.
Piroxicam
Adverse Effect: Decreased antihypertensive effect Clinical Management: If concurrent therapy is required monitor the patients blood pressure carefully and assess the need for a dosage adjustment for the beta blocker.
Prazosin - BPH
Adverse Effect: An exaggerated hypotensive response to the first dose of the alpha blocker Clinical Management: When concurrent therapy with an alpha blocker and a beta blocker is required initiate the alpha blocker with a smaller than usual dose preferably at bedtime. Monitor the patient closely for hypotension.
Tenoxicam
Adverse Effect: Decreased antihypertensive effect Clinical Management: If concurrent therapy is required monitor the patients blood pressure carefully and assess the need for a dosage adjustment for the beta blocker.
Terazosin - BPH
Adverse Effect: An exaggerated hypotensive response to the first dose of the alpha blocker Clinical Management: When concurrent therapy with an alpha blocker and a beta blocker is required initiate the alpha blocker with a smaller than usual dose preferably at bedtime. Monitor the patient closely for hypotension.
Verapamil
Adverse Effect: Hypotension bradycardia Clinical Management: If concurrent therapy is required monitor cardiac function carefully particularly in patients predisposed to heart failure.
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