Amitriptyline
Adverse Effect: Attenuation of antidepressant effectiveness; Amitriptyline toxicity (drowsiness, hypotension, akathisia) Clinical Management: If signs or symptoms of altered Amitriptyline response are noted, dose adjustment downward of either Dienoestrol or Amitriptyline may be successful in restoring effectiveness or resolving toxicity. However, drug withdrawal may be required.
Amoxapine
Adverse Effect: Attenuation of antidepressant effectiveness; tricyclic toxicity (drowsiness, hypotension, akathisia) Clinical Management: If signs or symptoms of altered Amoxapine response is noted, dose adjustment downward of either Dienoestrol or Amoxapine may be successful in restoring effectiveness or resolving toxicity. However, drug withdrawal may be required.
Chlordiazepoxide
Adverse Effect: Attenuation of antidepressant effectiveness; tricyclic toxicity (drowsiness, hypotension, akathisia) Clinical Management: If signs or symptoms of altered tricyclic response are noted, dose adjustment downward of either Dienoestrol or Chlordiazepoxide may be successful in restoring effectiveness or resolving toxicity. However, drug withdrawal may be required.
Clomipramine
Adverse Effect: attenuation of antidepressant effectiveness; tricyclic toxicity (drowsiness, hypotension, akathisia) Clinical Management: If signs or symptoms of altered tricyclic response are noted, dose adjustment downward of either Dienoestrol or Clomipramine may be successful in restoring effectiveness or resolving toxicity. However, drug withdrawal may be required.
Dothiepin
Adverse Effect: attenuation of antidepressant effectiveness; tricyclic toxicity (drowsiness, hypotension, akathisia) Clinical Management: If signs or symptoms of altered tricyclic response are noted, dose adjustment downward of either Dienoestrol or Dothiepin may be successful in restoring effectiveness or resolving toxicity. However, drug withdrawal may be required.
Doxepin
Adverse Effect: attenuation of antidepressant effectiveness; tricyclic toxicity (drowsiness, hypotension, akathisia) Clinical Management: If signs or symptoms of altered tricyclic response are noted, dose adjustment downward of either Dienoestrol or Doxepin may be successful in restoring effectiveness or resolving toxicity. However, drug withdrawal may be required.
Imipramine
Adverse Effect: Attenuation of antidepressant effectiveness; Imipramine toxicity (drowsiness, hypotension, akathisia) Clinical Management: If signs or symptoms of altered Imipramine response is noted, dose adjustment downward of either Dienoestrol or Imipramine may be successful in restoring effectiveness or resolving toxicity. However, drug withdrawal may be required.
Nitroxazapine
Adverse Effect: attenuation of antidepressant effectiveness; tricyclic toxicity (drowsiness, hypotension, akathisia) Clinical Management: If signs or symptoms of altered tricyclic response are noted, dose adjustment downward of either Dienoestrol or Nitroxazapine may be successful in restoring effectiveness or resolving toxicity. However, drug withdrawal may be required.
Nortriptyline
Adverse Effect: Attenuation of antidepressant effectiveness; tricyclic toxicity (drowsiness, hypotension, akathisia) Clinical Management: If signs or symptoms of altered Nortriptyline response are noted, dose adjustment downward of either Dienoestrol or Nortriptyline may be successful in restoring effectiveness or resolving toxicity. However, drug withdrawal may be required.
Trimipramine
Adverse Effect: attenuation of antidepressant effectiveness; tricyclic toxicity (drowsiness, hypotension, akathisia) Clinical Management: If signs or symptoms of altered tricyclic response are noted, dose adjustment downward of either Dienoestrol or Trimipramine may be successful in restoring effectiveness or resolving toxicity. However, drug withdrawal may be required. |