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	| Interactions: |  Gentamicin
Adverse Effect: Loss of Gentamicin efficacy     Clinical Management: Monitor patients for Gentamicin effectiveness. 
Methotrexate
Adverse Effect: an increased risk of methotrexate toxicity     Clinical Management: Avoid the concurrent use of methotrexate and penicillin if possible. If concomitant therapy is unavoidable, consider decreasing the methotrexate dose. 
Neomycin
Adverse Effect: Loss of Neomycin efficacy     Clinical Management: Monitor patients for Neomycin effectiveness. 
Netilmicin
Adverse Effect: Loss of Netilmicin efficacy     Clinical Management: Monitor patients for Netilmicin effectiveness. 
Sisomicin
Adverse Effect: Loss of Sisomicin efficacy     Clinical Management: Monitor patients for Sisomicin effectiveness. 
Streptomycin
Adverse Effect: Loss of Streptomycin efficacy     Clinical Management: Monitor patients for Streptomycin effectiveness. 
Tobramycin
Adverse Effect: Loss of Tobramycin efficacy     Clinical Management: Monitor patients for Tobramycin effectiveness.  |  
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